INHIBITION OF PROTEIN N-GLYCOSYLATION BLOCKS SARS-COV-2 INFECTION

Inhibition of Protein N-Glycosylation Blocks SARS-CoV-2 Infection

ABSTRACT Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) extensively N-glycosylates its Media Control Panel spike proteins, which are necessary for host cell invasion and the target of both vaccines and immunotherapies.These N-glycans are predicted to modulate spike binding to the host receptor by stabilizing its open conformation and

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Deep Learning-Based Semantic Segmentation for Legal Texts: Unveiling Rhetorical Roles in Legal Case Documents

The swift rise of digitization in legal documentation has opened doors for artificial intelligence to revolutionize various tasks within the legal domain.Among these tasks is the segmentation of legal documents using rhetorical labels.This process, known as rhetorical role labeling, involves assigning labels (such as Final Judgment, Argument, Fact,

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Numerical Simulation of Tectonic Stress State Considering The Multiscale Heterogeneity of Geological Structures

The development and utilization of deep underground is known to cause induced seismicity that could inflict devastating damage and pose a serious risk for safety and production.Notwithstanding the effort made in the past, a difficulty still lies in estimating the risk for induced seismicity especially taking place in geological structures.To addres

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